| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | @ Navy | 101 | 58.03 | 49 - 7 |
| 2021-09-11 | NC Central | 235 | 99.09 | 44 - 10 |
| 2021-09-18 | East Carolina | 97 | 71.19 | 38 - 42 |
| 2021-09-23 | @ Appalachian St | 47 | 31.99 | 30 - 31 |
| 2021-10-02 | @ MTSU | 115 | 70.16 | 28 - 34 |
| 2021-10-09 | Old Dominion | 147 | 86.73 | 20 - 13 |
| 2021-10-15 | @ North Texas | 153 | 78.45 | 49 - 21 |
| 2021-10-30 | Florida Intl | 166 | 91.87 | 38 - 0 |
| 2021-11-06 | @ FL Atlantic | 79 | 55.26 | 28 - 13 |
| 2021-11-13 | UAB | 87 | 77.80 | 14 - 21 |
| 2021-11-20 | @ Charlotte | 153 | 85.04 | 49 - 28 |
| 2021-11-27 | WKU | 33 | 45.83 | 21 - 53 |