| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | @ Georgia St | 95 | 58.09 | 43 - 10 |
| 2021-09-11 | WKU | 106 | 81.31 | 38 - 35 |
| 2021-09-18 | Connecticut | 203 | 97.38 | 52 - 21 |
| 2021-09-25 | Miami OH | 105 | 75.96 | 23 - 10 |
| 2021-10-02 | @ Ball St | 101 | 63.87 | 16 - 28 |
| 2021-10-16 | @ Wisconsin | 31 | 24.81 | 14 - 20 |
| 2021-10-23 | Wake Forest | 43 | 43.39 | 56 - 70 |
| 2021-11-06 | Air Force | 42 | 35.15 | 0 - 0 |
| 2021-11-13 | Bucknell | 256 | 99.76 | 63 - 10 |
| 2021-11-20 | Massachusetts | 240 | 98.47 | 33 - 17 |
| 2021-11-27 | @ Liberty | 76 | 38.26 | 31 - 16 |
| 2021-12-11 | Navy | 93 | 62.22 | 0 - 0 |