| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | Akron | 197 | 98.88 | 60 - 10 |
| 2021-09-11 | Alabama St | 225 | 99.41 | 62 - 0 |
| 2021-09-18 | @ Penn St | 8 | 34.20 | 20 - 28 |
| 2021-09-25 | Georgia St | 111 | 93.16 | 34 - 24 |
| 2021-10-02 | @ LSU | 16 | 37.54 | 24 - 19 |
| 2021-10-09 | Georgia | 2 | 19.35 | 10 - 34 |
| 2021-10-16 | @ Arkansas | 25 | 45.18 | 38 - 23 |
| 2021-10-30 | Mississippi | 7 | 48.20 | 31 - 20 |
| 2021-11-06 | @ Texas A&M | 11 | 45.06 | 3 - 20 |
| 2021-11-13 | Mississippi St | 30 | 68.39 | 34 - 43 |
| 2021-11-20 | @ South Carolina | 85 | 74.90 | 17 - 21 |
| 2021-11-27 | Alabama | 3 | 21.88 | 0 - 0 |