| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-02 | @ Chattanooga | 163 | 47.48 | 30 - 20 |
| 2021-09-11 | @ Mississippi | 24 | 3.84 | 17 - 54 |
| 2021-09-18 | Morehead St | 253 | 97.04 | 59 - 35 |
| 2021-09-25 | @ E Kentucky | 169 | 50.49 | 27 - 35 |
| 2021-10-02 | Tennessee St | 236 | 91.14 | 22 - 24 |
| 2021-10-09 | SE Missouri St | 190 | 61.87 | 14 - 30 |
| 2021-10-23 | @ Murray St | 181 | 39.35 | 47 - 6 |
| 2021-10-30 | @ TN Martin | 144 | 36.88 | 16 - 17 |
| 2021-11-06 | E Illinois | 239 | 90.31 | 42 - 26 |
| 2021-11-13 | @ Tennessee St | 203 | 67.20 | 36 - 7 |
| 2021-11-20 | Tennessee Tech | 241 | 92.63 | 48 - 20 |