| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | @ Idaho St | 168 | 69.94 | 35 - 14 |
| 2021-09-10 | @ Utah St | 113 | 43.38 | 24 - 48 |
| 2021-09-18 | Drake | 238 | 95.96 | 38 - 0 |
| 2021-10-02 | N Dakota St | 73 | 31.28 | 10 - 16 |
| 2021-10-09 | @ South Dakota | 122 | 46.10 | 13 - 20 |
| 2021-10-16 | @ S Illinois | 98 | 30.62 | 28 - 31 |
| 2021-10-23 | W Illinois | 177 | 81.25 | 34 - 10 |
| 2021-10-30 | @ Missouri St | 103 | 40.35 | 28 - 32 |
| 2021-11-06 | Youngstown St | 179 | 86.24 | 24 - 21 |
| 2021-11-13 | Illinois St | 138 | 67.78 | 14 - 7 |
| 2021-11-20 | @ S Dakota St | 62 | 19.12 | 21 - 24 |