| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | Prairie View | 208 | 15.84 | 17 - 40 |
| 2021-09-11 | @ Baylor | 60 | 0.31 | 7 - 66 |
| 2021-09-25 | @ Rice | 132 | 2.26 | 34 - 48 |
| 2021-10-09 | Southern Univ | 198 | 14.80 | 0 - 0 |
| 2021-10-16 | @ Grambling | 216 | 23.44 | 20 - 34 |
| 2021-10-23 | Alcorn St | 184 | 19.12 | 27 - 44 |
| 2021-10-30 | Ark Pine Bluff | 238 | 49.64 | 59 - 17 |
| 2021-11-06 | @ Jackson St | 148 | 11.88 | 21 - 41 |
| 2021-11-13 | Alabama A&M | 201 | 42.91 | 49 - 52 |
| 2021-11-20 | @ Alabama St | 225 | 43.50 | 21 - 24 |