| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | @ Kentucky | 35 | 2.59 | 10 - 45 |
| 2021-09-18 | Jackson St | 221 | 78.79 | 12 - 7 |
| 2021-09-25 | Troy | 92 | 12.52 | 29 - 16 |
| 2021-10-02 | @ Coastal Car | 43 | 4.41 | 6 - 59 |
| 2021-10-09 | Georgia St | 119 | 27.11 | 21 - 55 |
| 2021-10-16 | Liberty | 29 | 3.91 | 31 - 28 |
| 2021-10-23 | South Alabama | 115 | 27.72 | 41 - 31 |
| 2021-10-30 | @ Appalachian St | 50 | 8.59 | 28 - 59 |
| 2021-11-06 | @ Texas St | 171 | 52.56 | 19 - 27 |
| 2021-11-13 | Arkansas St | 167 | 63.40 | 24 - 27 |
| 2021-11-20 | @ LSU | 33 | 4.82 | 14 - 27 |
| 2021-11-27 | @ Louisiana | 32 | 6.24 | 16 - 21 |