| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | @ Sacred Heart | 200 | 18.29 | 0 - 21 |
| 2021-09-11 | @ Villanova | 131 | 4.14 | 3 - 55 |
| 2021-09-18 | Penn | 222 | 33.78 | 6 - 30 |
| 2021-10-02 | Cornell | 204 | 19.61 | 21 - 10 |
| 2021-10-09 | @ Lafayette | 211 | 23.03 | 0 - 27 |
| 2021-10-16 | @ Fordham | 177 | 9.94 | 21 - 66 |
| 2021-10-23 | Georgetown | 249 | 52.06 | 21 - 29 |
| 2021-10-30 | @ Colgate | 245 | 26.51 | 10 - 33 |
| 2021-11-06 | Lehigh | 250 | 41.52 | 6 - 38 |
| 2021-11-13 | @ Army | 58 | 0.24 | 10 - 63 |
| 2021-11-20 | Holy Cross | 135 | 2.32 | 6 - 45 |