| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-02 | Citadel | 191 | 97.03 | 52 - 14 |
| 2021-09-10 | Kansas | 136 | 90.86 | 49 - 22 |
| 2021-09-18 | @ Buffalo | 68 | 51.56 | 28 - 25 |
| 2021-09-25 | Massachusetts | 194 | 97.46 | 53 - 3 |
| 2021-10-02 | ULM | 166 | 95.59 | 59 - 6 |
| 2021-10-07 | @ Arkansas St | 123 | 86.61 | 52 - 20 |
| 2021-10-20 | @ Appalachian St | 57 | 64.91 | 27 - 30 |
| 2021-10-28 | Troy | 121 | 91.32 | 35 - 28 |
| 2021-11-06 | @ Ga Southern | 147 | 88.74 | 28 - 8 |
| 2021-11-13 | Georgia St | 105 | 83.22 | 40 - 42 |
| 2021-11-20 | Texas St | 173 | 94.63 | 35 - 21 |
| 2021-11-26 | @ South Alabama | 138 | 78.64 | 27 - 21 |