| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-08-28 | @ Indiana St | 147 | 14.64 | 21 - 26 |
| 2021-09-04 | @ South Carolina | 76 | 2.84 | 0 - 46 |
| 2021-09-11 | @ Dayton | 231 | 60.06 | 10 - 17 |
| 2021-09-18 | Illinois St | 145 | 21.15 | 24 - 31 |
| 2021-09-25 | @ Tennessee Tech | 226 | 57.54 | 28 - 14 |
| 2021-10-02 | @ Murray St | 186 | 30.13 | 6 - 22 |
| 2021-10-16 | TN Martin | 133 | 23.82 | 17 - 28 |
| 2021-10-23 | Tennessee St | 229 | 67.80 | 0 - 28 |
| 2021-10-30 | @ SE Missouri St | 185 | 18.14 | 15 - 38 |
| 2021-11-06 | @ Austin Peay | 153 | 9.69 | 26 - 42 |
| 2021-11-20 | Murray St | 196 | 36.35 | 13 - 20 |