| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | Gardner Webb | 227 | 98.23 | 30 - 25 |
| 2021-09-11 | @ FL Atlantic | 87 | 37.14 | 6 - 38 |
| 2021-09-18 | @ Arkansas | 31 | 11.79 | 10 - 45 |
| 2021-09-25 | Louisiana | 57 | 23.57 | 20 - 28 |
| 2021-10-02 | Arkansas St | 116 | 57.01 | 59 - 33 |
| 2021-10-09 | @ Troy | 105 | 41.76 | 24 - 27 |
| 2021-10-14 | @ South Alabama | 132 | 58.97 | 14 - 41 |
| 2021-10-30 | Georgia St | 120 | 41.02 | 14 - 21 |
| 2021-11-06 | Coastal Car | 34 | 11.26 | 8 - 28 |
| 2021-11-13 | @ Texas St | 165 | 49.54 | 38 - 30 |
| 2021-11-20 | BYU | 32 | 11.78 | 17 - 34 |
| 2021-11-27 | @ Appalachian St | 19 | 5.09 | 3 - 27 |